Can you use vitamin C with niacinamide?
Yes. The idea that they cancel each other out comes from 1960s research on unstable raw ingredients at high heat, not from finished modern formulas.
What Vessa does with both on your shelf
Vessa puts vitamin C in the morning and is content to schedule niacinamide in the same session.
Why
The old objection was that the two react to form niacin and cause flushing. That required conditions a cosmetic formula does not meet, and the products sold today are stabilised. Plenty of serums contain both.
Questions people ask next
How this answer is decided
These verdicts are the rules Vessa applies when it builds a routine, not an editorial opinion. The app schedules retinoids in the evening only, keeps exfoliants on different nights from them, puts vitamin C in the morning and sunscreen last every morning, and removes retinoids, salicylic acid and hydroquinone from consideration entirely when someone tells it they are pregnant or breastfeeding. Where the evidence is genuinely mixed, the app takes the cautious side and this page says so rather than picking one for you.
Vessa sells a subscription, not the products it recommends, and it suggests buying something only where a step is missing from what you already own. This is skincare guidance, not medical advice: anything painful, spreading or changing quickly belongs with a dermatologist.
Checked against your actual shelf
Scan the products you own and Vessa schedules them around each other, including this pair.